Paramus Cloud
Chemistry computation as a service. Use Paramus skills from Claude, or ChatGPT without installing anything on your machine.
Paramus Cloud provides a hosted subset of the Chemistry OS platform. It exposes ~330 chemistry skills through the Model Context Protocol (MCP), so any compatible AI assistant can run validated calculations instead of guessing.
For workloads that require GPU inference or full HPC capacity, the on-premise Chemistry OS provides the complete stack with BRAIN, WORLD, and OPERATE modules.
Free / $5
Access to the Paramus Cloud skill catalog (~330 skils) from Claude.
Supported Channels
Paramus Cloud connects to the AI assistants you already use. Each channel exposes the same chemistry skill catalog through different integration points.
ChatGPT / OpenAI
Use Paramus chemistry skills directly inside ChatGPT. The OpenAI connector routes prompts through the Paramus computation stack and returns validated results. No local installation required.
Claude
Connect local Paramus to local Claude Desktop. Claude gains access to 1213 chemistry skills! Including molecular property prediction, reaction planning, and spectroscopy analysis.
VSCode / Copilot
Paramus integrates as an MCP server into VSCode. GitHub Copilot and other AI assistants can call chemistry tools directly from the editor, with results returned in under 100 ms.
What You Get
Chemistry Skills
Molecular property prediction, reaction optimization, spectroscopy, thermodynamics, kinetics, polymer design, and more. Each skill is a validated computation, not a language guess.
~100 ms Response Time (local), ~350 ms (cloud)
Cloud-hosted inference returns results fast enough for interactive use. Complex simulations that require HPC are queued and returned asynchronously.
No Installation Required
For ChatGPT users the entire stack runs in the cloud. Claude and VSCode users install a lightweight MCP server that connects to the Paramus Cloud backend.
Data Sovereignty Option
Sensitive data? Switch to the on-premise Chemistry OS at any time. Cloud and local installations share the same API surface and skill catalog.
Cloud vs Chemistry OS
Paramus Cloud
- No installation, browser-based
- ~330 chemistry skills via MCP
- ChatGPT, Claude, VSCode support
- $10/month subscription (beta)
- Ideal for quick analyses and teaching
Chemistry OS (On-Premise)
- Full local installation on Windows
- ~1250 chemistry skills via MCP
- INTENT + WORLD + BRAIN + OPERATE
- Robotic and instrument integration
- Full data sovereignty, air-gapped capable
FAQ
Chemistry computation as a service. Access Paramus Brain engines, World knowledge graphs, and chemistry tools from Claude, ChatGPT, or any MCP-compatible AI assistant without installing software.
Install the Paramus MCP server in your AI client (Claude Desktop, VS Code, or Cursor). The MCP server connects to Paramus Cloud endpoints automatically. No local HPC installation needed.
Chemistry OS runs everything locally on Windows with full BRAIN, WORLD, OPERATE, and INTENT modules. Cloud provides a hosted subset accessible from any OS via AI assistants, without local installation.
Molecular property predictions, geometry optimizations, energy calculations, spectroscopy predictions, dataset queries, and knowledge graph operations. Supported engines include xTB, machine learning potentials, and RDKit.
A free tier is available with access to basic tools and the World knowledge graph. Professional and enterprise plans add full BRAIN engine access, higher computation limits, and priority support.