Tinker
Computing Applications (HPC) Tinker License – academic free (Partial)
About
A package for molecular mechanics and dynamics, known for its support of advanced polarizable force fields (AMOEBA). It provides tools for geometry optimization, molecular dynamics, and free energy calculations.
Key Features
- Force fields: AMOEBA, OPLS, MM3, CHARMM
- Polarization: induced dipole, Drude
- Methods: minimize, dynamics, analyze
- Free energy: BAR, thermodynamic integration
Free for academic/non-profit. Commercial license required.
Citation
Rackers, J.A. et al. Tinker 8: Software Tools for Molecular Design. J. Chem. Theory Comput. 14, 5273-5289 (2018). DOI:10.1021/acs.jctc.8b00529
Frequently Asked Questions
What is Tinker?
Tinker is a computing applications (hpc) application available in the Paramus App Store. A package for molecular mechanics and dynamics, known for its support of advanced polarizable force fields (AMOEBA). It provides tools for geometry optimization, molecular dynamics, and free energy calculations.
Is Tinker free to use?
Yes. Tinker is distributed under the Tinker License – academic free (Partial) license and is available at no cost through the Paramus App Store.
How do I install Tinker?
Tinker is installed through Paramus Chemistry OS, an on-premise Windows platform for computational chemistry. Open the Paramus App Store in your local installation and select Tinker for one-click deployment.
What are the key features of Tinker?
Key features of Tinker include: Force fields: AMOEBA, OPLS, MM3, CHARMM; Polarization: induced dipole, Drude; Methods: minimize, dynamics, analyze; Free energy: BAR, thermodynamic integration.
What type of application is Tinker?
Tinker belongs to the “Computing Applications (HPC)” category in the Paramus App Store. It runs on Paramus Chemistry OS and can also be accessed through Paramus Cloud for supported workflows.
What platform does Tinker run on?
Tinker runs on Paramus Chemistry OS, a Windows-based on-premise platform that provides local compute power for demanding simulations. It requires a Paramus OS installation with appropriate hardware resources.
Can Tinker be automated or integrated with AI workflows?
Yes. Tinker is available as part of the Paramus ecosystem which supports MCP (Model Context Protocol) tools for AI-driven automation. This enables integration with large language models and automated research pipelines.
How should I cite Tinker in publications?
The recommended citation for Tinker is: Rackers, J.A. et al. Tinker 8: Software Tools for Molecular Design. J. Chem. Theory Comput. 14, 5273-5289 (2018). DOI:10.1021/acs.jctc.8b00529