Paramus
Chemistry for AI
Paramus turns Claude, Copilot, and ChatGPT into true chemistry engines – verified atoms, validated reactions, and trustworthy computations from kinetics to DFT, without hallucinations.
Reproducible calculations, not an AI’s opinion
Incredible fast: ~100 ms response time on a standard laptop. Download → Install → Use for Claude and vsCode.
Paramus is free. Optional in-app purchases provide access to specialized chemistry applications. There is a marketplace for ‘classic’ AI models, cheminformatics, and data.
Also available for ChatGPT
For openAI you can use our Cloud version*
*) ChatGPT connectors are still beta … not ours


Optional Packages
Polymer Chemistry

AI-powered design of polymers and processes. Accelerate discovery with AI models and agent-driven process optimization.

Medicinal Chemistry


Predict properties, optimize reactions, and accelerate drug discovery with multi-agent workflows and secure local inference.
Material Science

Inverse design of new materials with AI + simulation tools (ORCA, LAMMPS, AIMNet2, MatterGen).

Products and Marketplaces
Run classical AI, LLMs, and heavy codes in one local architecture. Paramus Brain ensures reproducibility and IP safety.
AI Model and HPC Server
BRAIN
Load and install from public AI models to high-performence computational packges. Use local LLM without risk.

To install the models you need the Brain server: Learn more →
Semantic Information Server
WORLD
A semantic knowledge layer that ensures traceability, reproducibility, and contextual understanding of every information that is connected.

To install the data packages you need the World server: Learn more →
AI Agent
With AI Agents users gain intelligent companions that guide workflows, assist in decision-making, and bridge human expertise with machine intelligence.
The AI agent need Paramus to be installed.
Why a Chemistry Runtime for Agents?
You are builing agentic systems (LLMs, robotics, autonomous R&D pipelines) that need:
- physical-world (‘chemical-world’) guardrails.
- validated chemical knowledge
- structured ontologies
- simulation interfaces
- data products and model plug-ins

Free for Academia
Paramus is available at no cost for academic research.
We ask for error reporting and contributions to agent development.
ISO 42001 Compliant
We provide an free audit-secure bookkeeping package, pre-filled with Paramus AI model documentation, enabling traceable evidence for ISO 42001 conformity. Particularly relevant for the EU, this keeps your organisation on the safe side. Paramus is regulatory ready for both professional and academic deployment.

Using AI solutions without documentation – also as cloud service – is a compliance risk. Paramus makes you ISO 42001-safe, audit-proof, and ready for the EU. Of course, you can also manage all your AI compliance matters – including for competitor systems and non-chemistry use cases – within this bookkeeping solution.
We transform todays fragmented simulations, chemical AI models, and data landscape into a unified, usable, and evolving ecosystem.
A fundamental flip: chemical expertise is no longer packaged for human consumption first, but for machine consumption. Humans interact through any Copilot or OpenAI Agent, and Paramus ensures the results remain chemically correct.
Thorsten Gressling, Founder & CEO
